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This study aims to demonstrate the capability of optical coherence tomography (OCT) for high-resolution imaging of arterial tissue in vivo.

August 1, 1999HeartOpen Access

High resolution in vivo intra-arterial imaging with optical coherence tomography

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This study aims to demonstrate the capability of optical coherence tomography (OCT) for high-resolution imaging of arterial tissue in vivo.
OCT imaging of the abdominal aorta using a 2.9 F OCT imaging catheter
An ultrashort pulse laser was utilized as the light source to achieve 10 micrometer axial resolution
Saline injections were implemented to counteract signal attenuation from blood during imaging.
Imaging was performed at a rate of 4 frames/second with data saved in super VHS or digital format
Microstructure within the arterial wall was clearly defined and correlated with histological findings
Motion artefacts were observed but did not significantly impede the overall imaging quality.

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Randomized trial demonstrates high resolution imaging of arterial tissue, highlighting potential for improved intervention guidance.

Fujimoto et al. (1999) studied this question.

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