Key result
ACTN3 R577X genotype distribution was similar between amateur soccer players and sedentary controls and had no significant effect on sprint and endurance characteristics.
Why the study?
The study was conducted to determine the distribution of the ACTN3 R577X gene polymorphism in soccer players and sedentary individuals and investigate its relationship with physical performance tests.
Does the ACTN3 R577X gene polymorphism affect physical performance in amateur soccer players compared to sedentary individuals?
Case-Control (n=201)
No
Does the ACTN3 R577X gene polymorphism affect physical performance in amateur soccer players compared to sedentary individuals?
p-value: p=>0.05
The ACTN3 R577X polymorphism does not significantly affect sprint and endurance characteristics in amateur soccer players, suggesting it is not a specific enough genetic marker to determine athletic performance in this population.
No link to performance in amateurs; leaves open utility for elite selection or training response.
The aim of this study was to determine the distribution of ACTN3 R577X gene polymorphism in soccer players and sedentary individuals, and to investigate the relationship of this distribution with performance tests. A total of 100 soccer players and 101 sedentary individuals were enrolled in the study. Standing long jump and countermovement jump (with arm swing, without arm swing and repeated) scores were recorded, using a jump meter. Maximum VO 2 levels were measured using a treadmill-connected cardiopulmonary exercise device, Masterscreen CPX. ACTN3 R577X polymorphism was evaluated by real-time PCR. ACTN3 R577X genotype distribution was found to be similar in soccer players and controls (p>0.05). The only statistically significant finding was a shorter countermovement jump with arm swing scores in the RR-genotyped soccer players, compared with their RX genotyped counterparts (p<0.05). In the soccer player group, RX-genotyped subjects were observed to have lower respiratory threshold values compared with RR-genotyped subjects (p<0.05). No significant correlation was detected between this distribution and performance test results. ACTN3 R577X genotype distribution was found to have no effect on sprint and endurance characteristics in amateur soccer players. The ACTN3 R577X polymorphism may not be a specific enough genetic marker to determine athletic performance in soccer.
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Koku et al. (2018) conducted a case-control in Healthy amateur soccer players and sedentary individuals (n=201). ACTN3 R577X gene polymorphism vs. Sedentary individuals was evaluated on ACTN3 R577X genotype distribution (p=>0.05). ACTN3 R577X genotype distribution was similar between amateur soccer players and sedentary controls and had no significant effect on sprint and endurance characteristics.
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