April 1, 2002Blood Pressure Monitoring
Uncontrolled early morning blood pressure in medicated patients: the ACAMPA study
Key result
Among medicated hypertensive patients, high blood pressure during the second hour after waking occurred in 82% of those with poor office BP control and 62% of those with good office BP control.
Why the study?
What is the profile of early morning blood pressure in patients receiving antihypertensive treatment?
Population
290 patients with essential hypertension who had been receiving the same antihypertensive treatment for at…
Design
Cohort, open
Authors
Discussion
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Implication
Many treated hypertensives show uncontrolled morning BP; leaves open whether targeting the surge improves outcomes.
Study Design
Type
Observational (n=290)
Blinding
Open-label
Multicenter
Yes
Structured PICO
What is the profile of early morning blood pressure in patients receiving antihypertensive treatment?
P
Population
290 patients with essential hypertension on stable antihypertensive treatment for at least 2 months, evaluated for early morning blood pressure control.
E
Exposure
Antihypertensive treatment for at least 2 months
O
Outcome
Blood pressure behaviour profile of early morning blood pressure assessed via office blood pressure and 24-h ambulatory blood pressure monitoringsurrogate
Main Result
Absolute Event Rate: 82% vs 62%
A significant proportion of treated hypertensive patients, including those with well-controlled office blood pressure, exhibit uncontrolled early morning blood pressure.
Cite This Study
Redón et al. (2002) conducted an observational in Essential hypertension (n=290). Poor office blood pressure control vs. Good office blood pressure control was evaluated on High blood pressure values during the second hour after waking. Among medicated hypertensive patients, high blood pressure during the second hour after waking occurred in 82% of those with poor office BP control and 62% of those with good office BP control.