Expression of angiotensinogen and receptors for angiotensin and prorenin in the monkey and human substantia nigra: an intracellular renin–angiotensin system in the nigra

Garrido‐Gil et al. (2012) conducted an observational in Healthy (no neurological disease) (n=7). Expression of renin-angiotensin system components was evaluated on Localization of RAS components in substantia nigra. Major components of the renin-angiotensin system are expressed at the cell surface and intracellularly in dopaminergic neurons and glial cells of the monkey and human substantia nigra.