Key result
Mid-pregnancy was associated with significantly lower heart rate variability and blunted cardiovascular responses to autonomic tests compared with nonpregnant women.
Why the study?
Does mid-pregnancy alter cardiovascular autonomic reflexes compared to nonpregnant women?
Population
122 women, comprising 60 pregnant women at 22 to 29 weeks gestation and 62 nonpregnant women
Comparison
Mid-pregnancy (22 to 29 weeks gestation) vs Nonpregnant state (62 nonpregnant women)
Design
Cross-sectional
Authors
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Indicates autonomic modulation in normal pregnancy; hypothesis-generating for outcome links.
Cross-Sectional (n=122)
Does mid-pregnancy alter cardiovascular autonomic reflexes compared to nonpregnant women?
Mid-pregnancy is associated with blunted cardiovascular autonomic responses, indicating a decrease in parasympathetic cardiovascular control.
Ekholm et al. (1993) conducted a cross-sectional in Normal pregnancy (n=122). Mid-pregnancy (22 to 29 weeks gestation) vs. Nonpregnant women was evaluated on Physiological responses to noninvasive cardiovascular autonomic function tests. Mid-pregnancy was associated with significantly lower heart rate variability and blunted cardiovascular responses to autonomic tests compared with nonpregnant women.
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