Why the study?
Does mid-pregnancy alter autonomic cardiovascular control compared to non-pregnant controls?
Population
89 women, comprising 50 with singleton pregnancies and 39 non-pregnant female controls.
Comparison
Mid-pregnancy (physiological state/exposure) vs Non-pregnant state (healthy female controls)
Design
Case-control
Authors
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Should not change clinical management; hypothesis-generating for autonomic shifts in pregnancy.
Does mid-pregnancy alter autonomic cardiovascular control compared to non-pregnant controls?
Mid-pregnancy is associated with altered autonomic cardiovascular control, characterized by decreased parasympathetic tone and increased sympathetic tone at rest.
Ekholm et al. (1992) studied this question.
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