Key result
Intravascular ultrasound demonstrated that regressed coronary aneurysms in Kawasaki disease have markedly thickened intima, whereas angiographically normal sites mostly show normal wall morphology.
Why the study?
Does intravascular ultrasound imaging (IVUS) accurately assess coronary artery wall morphology and lumen structure in children after Kawasaki disease?
Population
20 subjects including 10 patients after Kawasaki disease with coronary aneurysms or regressed aneurysms, 2…
Comparison
Intravascular ultrasound imaging performed… vs Control patients with congenital heart disease…
Design
Cross-sectional
Authors
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IVUS detects subclinical intimal thickening in regressed aneurysms missed by angiography; hypothesis-generating for long-term ischemic risk in Kawasaki disease.
Observational (n=20)
Does intravascular ultrasound imaging (IVUS) accurately assess coronary artery wall morphology and lumen structure in children after Kawasaki disease?
Sugimura et al. (1994) conducted an observational in Kawasaki disease (n=20). Intravascular ultrasound imaging (IVUS) vs. Control patients with congenital heart disease and normal coronary arteries was evaluated on Coronary artery wall morphology and lumen characteristics. Intravascular ultrasound demonstrated that regressed coronary aneurysms in Kawasaki disease have markedly thickened intima, whereas angiographically normal sites mostly show normal wall morphology.
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