Key result
Coronary artery lesions long after Kawasaki disease exhibited higher absolute values of fibrous, dense calcium, and necrotic core areas compared to normal coronary segments.
Why the study?
Does virtual histology-intravascular ultrasound reveal atheroma-like features in coronary artery lesions long after Kawasaki disease compared to normal coronary segments?
Population
13 Japanese adolescents and young adults long after Kawasaki disease.
Comparison
Virtual histology-intravascular ultrasound… vs Normal coronary segments assessed by VH-IVUS.
Design
Cross-sectional
Authors
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Virtual histology-intravascular ultrasound demonstrates that coronary artery lesions late after Kawasaki disease exhibit atheroma-like plaque composition, particularly in areas of localized stenosis.
Observational (n=13)
Does virtual histology-intravascular ultrasound reveal atheroma-like features in coronary artery lesions long after Kawasaki disease compared to normal coronary segments?
Virtual histology-intravascular ultrasound demonstrates that coronary artery lesions late after Kawasaki disease exhibit atheroma-like plaque composition, particularly in areas of localized stenosis.
Mitani et al. (2009) conducted an observational in Kawasaki disease (n=13). Coronary artery lesions vs. Normal coronary segments was evaluated on Plaque composition and morphology (fibrous, fibrofatty, necrotic core, and dense calcium areas). Coronary artery lesions long after Kawasaki disease exhibited higher absolute values of fibrous, dense calcium, and necrotic core areas compared to normal coronary segments.
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