September 1, 1993Circulation
Concordance and discordance between stress-redistribution-reinjection and rest-redistribution thallium imaging for assessing viable myocardium. Comparison with metabolic activity by positron emission tomography.
Key result
Stress-redistribution-reinjection and rest-redistribution thallium imaging demonstrated 94% concordance for identifying viable myocardium when defect severity was considered.
Why the study?
Does stress-redistribution-reinjection thallium imaging provide concordant information regarding myocardial viability compared to rest-redistribution imaging in patients with chronic stable coronary artery disease?
Population
41 patients with chronic stable coronary artery disease
Comparison
Stress-redistribution-reinjection thallium… vs Rest-redistribution thallium single photon…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports protocol flexibility for viability assessment in stable CAD; leaves open need for outcome validation.
Study Design
Type
Observational (n=41)
Structured PICO
Does stress-redistribution-reinjection thallium imaging provide concordant information regarding myocardial viability compared to rest-redistribution imaging in patients with chronic stable coronary artery disease?
P
Population
41 patients with chronic stable coronary artery disease undergoing thallium single photon emission computed tomographic imaging.
E
Exposure
Stress-redistribution-reinjection thallium single photon emission computed tomographic imaging
C
Comparator
Rest-redistribution thallium single photon emission computed tomographic imaging
O
Outcome
Concordance of data regarding myocardial viability (normal/reversible or irreversible)surrogate
Stress-redistribution-reinjection and rest-redistribution thallium imaging provide highly concordant information for identifying viable myocardium, though stress imaging offers additional data on inducible ischemia.
Cite This Study
Dilsizian et al. (1993) conducted an observational in chronic stable coronary artery disease (n=41). Stress-redistribution-reinjection thallium imaging vs. Rest-redistribution thallium imaging was evaluated on Concordance regarding myocardial viability. Stress-redistribution-reinjection and rest-redistribution thallium imaging demonstrated 94% concordance for identifying viable myocardium when defect severity was considered.