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June 15, 2018CellsOpen Access

The TRPM4 channel plays a key role in cardiovascular pathophysiology, including cardiac conduction disease and the development of cardiac ischemia-reperfusion injury.

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Key result

The TRPM4 channel plays a key role in cardiovascular pathophysiology, including cardiac conduction disease and the development of cardiac ischemia-reperfusion injury.

Authors

CWChen WangKNKeiji NaruseKTKen Takahashi

Discussion

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Overview

TRPM4 mutations merit consideration in unexplained conduction disease; leaves open targeted modulator development pending mechanistic validation.

PICO

P
Population
Cardiovascular pathophysiology
E
Exposure / Comparator
TRPM4 channel

This review highlights the role of the TRPM4 channel in cardiovascular physiology and pathophysiology, including its involvement in cardiac conduction disease and ischemia-reperfusion injury.

Cite This Study

Wang et al. (2018) conducted a review in Cardiovascular pathophysiology. TRPM4 channel was evaluated. The TRPM4 channel plays a key role in cardiovascular pathophysiology, including cardiac conduction disease and the development of cardiac ischemia-reperfusion injury.

synapsesocial.com/papers/6a6c08db109fb9aed02454dbhttps://doi.org/10.3390/cells7060062
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Also Consider

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  4. 4Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration2024 · 12 citations
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