Contrast-induced kidney injury
Key result
Contrast-induced acute kidney injury was associated with significantly higher 8-year rates of major adverse cardiac and cerebrovascular events (54% vs 15%; RR 6.67, P<0.01).
Why the study?
Does contrast-induced acute kidney injury increase the risk of long-term cardiovascular adverse events in patients undergoing coronary angiography or PCI?
Population
980 patients undergoing coronary angiography or percutaneous coronary intervention (PCI)
Comparison
Contrast-induced acute kidney injury, defined as… vs Patients without contrast-induced acute kidney…
Design
Cohort
Follow-up
8 years
Authors
Discussion
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Member takes
Implication
May flag higher-risk patients for closer surveillance; leaves open whether CIAKI prevention reduces long-term MACCE.
Study Design
Type
Cohort (n=980)
Structured PICO
Does contrast-induced acute kidney injury increase the risk of long-term cardiovascular adverse events in patients undergoing coronary angiography or PCI?
P
Population
980 patients undergoing coronary angiography or percutaneous revascularization, followed for 8 years.
E
Exposure
Contrast-induced acute kidney injury (CIAKI), defined as serum creatinine increase at least 0.3 mg/dl in 48 h or at least 50% in 7 days
C
Comparator
Patients without contrast-induced acute kidney injury
O
Outcome
Major adverse cardiac and cerebrovascular events (MACCE) and cardiac death (CVD) during an 8-year follow-upcomposite
Main Result
Relative Risk: 6.67
Absolute Event Rate: 54% vs 15%
p-value: p=<0.01
Contrast-induced acute kidney injury after coronary angiography or PCI is strongly associated with an increased risk of long-term major adverse cardiac and cerebrovascular events and cardiac death.
Cite This Study
Andreis et al. (2017) conducted a cohort in Coronary angiography or percutaneous revascularization (n=980). Contrast-induced acute kidney injury (CIAKI) vs. No CIAKI was evaluated on Major adverse cardiac and cerebrovascular events (MACCE) (RR 6.67, p=<0.01). Contrast-induced acute kidney injury was associated with significantly higher 8-year rates of major adverse cardiac and cerebrovascular events (54% vs 15%; RR 6.67, P<0.01).