Key result
Toxic concentrations of antipsychotic and/or antidepressant drugs were identified as the probable cause of death in 5 of 8 cases of sudden unexplained death, usually involving cardiac arrhythmias.
Why the study?
Are toxic concentrations of antipsychotic and/or antidepressant drugs associated with sudden unexplained death?
Population
8 medico-legal cases of sudden unexplained death in patients on antipsychotic drug treatment
Design
Case_series
Authors
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May warrant drug level monitoring in unexplained deaths; leaves open causal link to antipsychotics.
Case Report (n=8)
Are toxic concentrations of antipsychotic and/or antidepressant drugs associated with sudden unexplained death?
Toxic concentrations of antipsychotics and/or antidepressants may cause sudden unexpected death via cardiac arrhythmias, highlighting the need for careful monitoring and simple drug regimens.
Jusic et al. (1994) conducted a case report in Sudden unexplained death (n=8). Antipsychotic and/or antidepressant drugs was evaluated on Toxic concentrations causing death. Toxic concentrations of antipsychotic and/or antidepressant drugs were identified as the probable cause of death in 5 of 8 cases of sudden unexplained death, usually involving cardiac arrhythmias.
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