Key result
A high CRP/ALB ratio immediately after ICU admission was associated with a 30% and 43% higher probability of 30-day and 1-year mortality, respectively, in postoperative patients (p < 0.05).
Why the study?
Does a high C-reactive protein to albumin ratio predict 30-day and 1-year mortality in postoperative patients admitted to the ICU?
Cohort (n=11,832)
No
Does a high C-reactive protein to albumin ratio predict 30-day and 1-year mortality in postoperative patients admitted to the ICU?
Effect estimate: 30% and 43% higher probability
p-value: p=< 0.05
The CRP/ALB ratio measured immediately after ICU admission is an independent prognostic marker for 30-day and 1-year mortality in postoperative critically ill patients.
CRP/ALB ratio may aid postoperative ICU risk stratification; hypothesis-generating and requires prospective validation before practice change.
C-reactive protein and albumin are associated with poor outcomes in critically ill patients. This study aimed to investigate the significance of the C-reactive protein/albumin (CRP/ALB) ratio as a novel prognostic factor for 30-day or 1-year mortality after admission to the postoperative intensive care unit (ICU). This retrospective study was conducted by examining the medical records of postoperative patients aged 19 years or older admitted to the ICU at a tertiary care hospital from January 2007 to July 2016. This study included data on 11,832 postoperative patients in the analysis. The cut-off value of the CRP/ALB ratio was set at 1.75 and 1.58 for 30-day and 1-year mortality after ICU admission, respectively. In postoperative patients with a high CRP/ALB ratio (>1.75 or >1.58), the probability of death within 30 days or 1 year after ICU admission were 30% or 43% higher than that in the group with the least CRP/ALB ratio, respectively (≤1.75 or ≤1.58)(p < 0.05). This study found the CRP/ALB ratio measured immediately after ICU admission to be an independent risk factor for 30-day and 1-year mortality in postoperative patients admitted to the ICU.
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Oh et al. (2018) conducted a cohort in Postoperative ICU admission (n=11,832). High C-reactive protein to albumin (CRP/ALB) ratio vs. Low CRP/ALB ratio (≤1.75 or ≤1.58) was evaluated on 30-day and 1-year mortality (30% and 43% higher probability, p=< 0.05). A high CRP/ALB ratio immediately after ICU admission was associated with a 30% and 43% higher probability of 30-day and 1-year mortality, respectively, in postoperative patients (p < 0.05).
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