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September 24, 2013Renal FailureOpen Access

Prolonged elevated postprandial sugar augments severity in kidney disease: a North Indian hospital-based study

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Why the study?

Are elevated postprandial sugar and systolic blood pressure associated with the severity of chronic kidney disease?

Population

317 individuals from North India, comprising 162 patients diagnosed with chronic kidney disease and 155…

Design

Case-control

Key result

Prolonged elevated postprandial blood sugar was strongly associated with increased odds of mild, moderate, and severe chronic kidney disease (severe CKD OR 7.610; 95% CI 4.03-14.36; p=0.000).

Authors

SCSubhash ChandraASAlok Kumar SinghMSM. Singh

Discussion

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Overview

May inform risk stratification in Indian CKD; leaves open causal roles and needs prospective validation before practice change.

Study Design

Type

Case-Control (n=317)

Multicenter

No

Structured PICO

Are elevated postprandial sugar and systolic blood pressure associated with the severity of chronic kidney disease?

P
Population
317 participants, including 162 patients with chronic kidney disease and 155 normal controls, evaluated at a North Indian hospital.
C
Comparator
Normal control group (n=155)
O
Outcome
Association of risk factors (glycemic indices, blood pressure, BMI, age) with CKD stagessurrogate

Main Result

Odds Ratio: 7.61 (95% CI 4.03–14.36)

p-value: p=0.000

Elevated postprandial blood sugar and systolic blood pressure are strong predictors of prevalent nephropathy and its severity in a North Indian population.

Cite This Study

Chandra et al. (2013) conducted a case-control in Chronic kidney disease (n=317). Prolonged elevated postprandial blood sugar vs. Normal postprandial blood sugar was evaluated on Severe CKD (OR 7.610, 95% CI 4.03-14.36, p=0.000). Prolonged elevated postprandial blood sugar was strongly associated with increased odds of mild, moderate, and severe chronic kidney disease (severe CKD OR 7.610; 95% CI 4.03-14.36; p=0.000).

synapsesocial.com/papers/6a6c1eca2ef98b0efacb7ed9https://doi.org/10.3109/0886022x.2013.832862
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