What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Healthy (n=132). Intervention: Absolute muscle strength (handgrip MVC) vs. Lower muscle strength. Primary outcome: Systolic, diastolic, and mean arterial pressure responses during static handgrip (p=<0.0005).

What question did this study set out to answer?

This research examines how absolute muscle strength affects blood pressure responses to static handgrip exercise, with a focus on potential sex differences.

November 11, 2017Medicine & Science in Sports & Exercise

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women

Q: What are the key findings of this study?

Men had larger blood pressure responses to static handgrip exercise than women (P 0.35).

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Key result

Men had larger blood pressure responses to static handgrip exercise than women (P<0.0005), but these differences were abolished after controlling for absolute handgrip strength (P>0.35).

Why the study?

Does absolute muscle strength influence blood pressure responses to static handgrip exercise in men and women?

Population

132 healthy participants (66 men and 66 women; age, 22 ± 3 yr)

Comparison

2 min of static handgrip at 30% maximal… vs Baseline rest; comparisons between men and…

Design

Cross-sectional

Follow-up

2 minutes

Authors

KNKarambir NotayUniversity of Guelph JLJordan B. LeeUniversity of Calgary AIAnthony V. IncognitoMemorial University of Newfoundland

Discussion

Member takes

Implication

Absolute strength may not drive sex differences in relative static exercise BP responses; leaves open its role in cross-sectional data interpretation.

Key Points

This research examines how absolute muscle strength affects blood pressure responses to static handgrip exercise, with a focus on potential sex differences.
132 healthy participants (66 men and 66 women) performed static handgrip at 30% MVC while BP and heart rate were continuously measured.
Comparisons were made between BP and heart rate responses in men and women, adjusted for baseline measurements and anthropometric differences.
Responses were analyzed within each sex by tertiles of handgrip MVC to assess how strength levels influenced BP.
Men exhibited significantly higher systolic, diastolic, and mean arterial pressure responses than women during static handgrip (P < 0.0005).
Adjusting for handgrip MVC negated the differences in BP responses between sexes (P > 0.35).
Within the lowest tertile of handgrip MVC, men had smaller BP responses (P < 0.006), while women in the highest tertile showed larger BP responses (P < 0.04).

Study Design

Type

Cross-Sectional (n=132)

Structured PICO

Does absolute muscle strength influence blood pressure responses to static handgrip exercise in men and women?

Population

132 healthy young adults (50% female, mean age 22 years) undergoing static handgrip exercise.

Exposure

2 min of static handgrip at 30% maximal voluntary contraction (MVC)

Comparator

Baseline rest; comparisons between men and women, and between tertiles of handgrip MVC

Outcome

Blood pressure (systolic, diastolic, mean arterial pressure) and heart rate responses during exercisesurrogate

Main Result

p-value: p=<0.0005

Absolute handgrip strength plays an important role in mediating the blood pressure response to static handgrip exercise, explaining observed sex-based differences.

Cite This Study

Notay et al. (2017) conducted a cross-sectional in Healthy (n=132). Absolute muscle strength (handgrip MVC) vs. Lower muscle strength was evaluated on Systolic, diastolic, and mean arterial pressure responses during static handgrip (p=<0.0005). Men had larger blood pressure responses to static handgrip exercise than women (P<0.0005), but these differences were abolished after controlling for absolute handgrip strength (P>0.35).

synapsesocial.com/papers/6a6c2dac547974b2dbf4821f https://doi.org/10.1249/mss.0000000000001485

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Implication

Absolute strength may not drive sex differences in relative static exercise BP responses; leaves open its role in cross-sectional data interpretation.

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider