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April 21, 2011AJP Regulatory Integrative and Comparative PhysiologyOpen Access

Sex differences in the modulation of vasomotor sympathetic outflow during static handgrip exercise in healthy young humans

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Why the study?

Are there sex differences in the modulation of vasomotor sympathetic outflow during static handgrip exercise in healthy young humans?

Population

21 healthy young humans (11 women and 10 men)

Comparison

Static handgrip to fatigue with 2 min of… vs Men vs. Women, and within women across menstrual…

Design

Other

Authors

SJSara S. JarvisNorthern Arizona UniversityTVTiffany B. VanGundyTexas Health DallasMGM GalbreathTexas Health Dallas

Discussion

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Overview

Women exhibit blunted sympathetic responses to static exercise independent of menstrual phase; hypothesis-generating and should not yet change practice.

Structured PICO

Are there sex differences in the modulation of vasomotor sympathetic outflow during static handgrip exercise in healthy young humans?

P
Population
21 healthy young humans (11 women and 10 men)
I
Intervention
Static handgrip to fatigue with 2 min of postexercise circulatory arrest (PECA) and cold pressor test (CPT)
C
Comparator
Men vs. Women, and within women across menstrual cycle phases (midluteal vs. early follicular)
O
Outcome
Heart rate (HR), blood pressure (BP), and muscle sympathetic nerve activity (MSNA)surrogate

Women demonstrate a blunted sympathetic vasomotor response to static exercise compared to men, which is not modulated by menstrual cycle phases.

Cite This Study

Jarvis et al. (2011) studied this question.

synapsesocial.com/papers/6a7162b1febe604dd70a0d9fhttps://doi.org/10.1152/ajpregu.00562.2010
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Also Consider

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