Key result
Biphasic waveform defibrillation required lower energy thresholds than monophasic for epicardial RV-LV (4.8 vs 6.7 J, p=0.047) and nonthoracotomy RV-CP systems (23.4 vs 34.3 J, p=0.0042).
Why the study?
Does biphasic waveform defibrillation improve defibrillation efficacy compared to monophasic waveform defibrillation in cardiac arrest survivors undergoing automatic defibrillator implantation?
Population
51 cardiac arrest survivors undergoing automatic defibrillator implantation
Comparison
Single capacitor biphasic waveform pulses vs Monophasic waveform pulses
Design
RCT, randomized
Authors
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Biphasic waveforms may aid defibrillation across lead systems; leaves open confirmation in larger outcome trials.
RCT (n=51)
Does biphasic waveform defibrillation improve defibrillation efficacy compared to monophasic waveform defibrillation in cardiac arrest survivors undergoing automatic defibrillator implantation?
Absolute Event Rate: 4.8% vs 6.7%
p-value: p=0.047
Biphasic waveform defibrillation is generally more efficient than monophasic defibrillation, but the degree of superiority depends on the specific electrode system used.
Bardy et al. (1991) conducted an RCT in Cardiac arrest (n=51). Biphasic waveform defibrillation vs. Monophasic waveform defibrillation was evaluated on Defibrillation threshold energy (Joules) for the epicardial RV-LV system (p=0.047). Biphasic waveform defibrillation required lower energy thresholds than monophasic for epicardial RV-LV (4.8 vs 6.7 J, p=0.047) and nonthoracotomy RV-CP systems (23.4 vs 34.3 J, p=0.0042).
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