Key result
A biphasic waveform significantly improved defibrillation efficacy at 20 J compared to a standard monophasic waveform (91% vs 76%) in patients receiving nonthoracotomy defibrillation leads.
Why the study?
Does a biphasic defibrillation waveform reduce defibrillation thresholds compared to a monophasic waveform in patients receiving nonthoracotomy defibrillation leads?
Population
79 patients receiving nonthoracotomy defibrillation leads intraoperatively.
Comparison
Biphasic defibrillation waveform delivered via… vs Standard monophasic defibrillation waveform…
Design
RCT, Randomized cross-over (waveforms used alternately).
Follow-up
Intraoperative
Authors
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Biphasic waveforms may improve nonthoracotomy defibrillation success; leaves open optimal configurations and long-term outcomes.
RCT (n=79)
Cross-over
Does a biphasic defibrillation waveform reduce defibrillation thresholds compared to a monophasic waveform in patients receiving nonthoracotomy defibrillation leads?
Absolute Event Rate: 91% vs 76%
Biphasic defibrillation waveforms significantly lower defibrillation thresholds and improve shock efficacy compared to monophasic waveforms in patients receiving nonthoracotomy ICD leads.
Block et al. (1994) conducted an RCT in Implantable cardioverter defibrillator implantation (n=79). Biphasic waveform vs. Standard monophasic waveform was evaluated on Defibrillation efficacy at 20 J. A biphasic waveform significantly improved defibrillation efficacy at 20 J compared to a standard monophasic waveform (91% vs 76%) in patients receiving nonthoracotomy defibrillation leads.
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