Key result
D-Dimer tests, particularly the SimpliRED test with 84-100% sensitivity and 92-99% negative predictive value, show promise for screening low-risk patients for pulmonary embolism.
Why the study?
Does D-Dimer testing accurately diagnose or rule out pulmonary embolism in suspected patients?
Population
Patients suspected of having pulmonary embolism
Design
Review
Authors
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May support selective D-dimer use in low-risk PE; leaves open need for prospective validation.
Does D-Dimer testing accurately diagnose or rule out pulmonary embolism in suspected patients?
D-Dimer tests, particularly newer bedside assays, show high sensitivity and negative predictive value, making them useful for screening low-risk patients to avoid unnecessary radiological investigations for pulmonary embolism.
Mountain et al. (1996) conducted a review in Pulmonary embolism. D-Dimer tests was evaluated on Diagnostic accuracy (sensitivity, specificity, negative predictive value). D-Dimer tests, particularly the SimpliRED test with 84-100% sensitivity and 92-99% negative predictive value, show promise for screening low-risk patients for pulmonary embolism.
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