Key result
Carotid intima-media thickness and ankle-brachial pressure index were independently associated with the presence of clinically manifest cardiovascular disease in subjects with type 2 diabetes.
Why the study?
Are measures of atherosclerotic burden associated with clinically manifest cardiovascular disease in subjects with type 2 diabetes?
Population
1,500 subjects including 458 with type 2 diabetes and cardiovascular disease, 527 with T2D without…
Design
Cross-sectional
Authors
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May refine CVD risk assessment in T2D; leaves open incremental value beyond standard factors in prospective studies.
Cross-Sectional (n=1,500)
Yes
Are measures of atherosclerotic burden associated with clinically manifest cardiovascular disease in subjects with type 2 diabetes?
Carotid intima-media thickness and ankle-brachial index are strong surrogate markers associated with clinically manifest cardiovascular disease in patients with type 2 diabetes.
Shore et al. (2015) conducted a cross-sectional in Type 2 diabetes (n=1,500). Atherosclerotic burden (carotid intima-media thickness and ankle-brachial pressure index) was evaluated on Clinically manifest cardiovascular disease (myocardial infarction, stroke or lower extremity arterial disease). Carotid intima-media thickness and ankle-brachial pressure index were independently associated with the presence of clinically manifest cardiovascular disease in subjects with type 2 diabetes.
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