Grid Radiation Therapy Based on Multileaf Collimator for Neoadjuvant Treatment of Large-Volume Intrahepatic Cholangiocarcinoma: A Case Report

Intrahepatic cholangiocarcinoma (ICC) incidence has risen globally in recent years. It has a high mortality rate and poor prognosis due to its insidious onset. Surgical resection remains the cornerstone for long-term survival. However, some patients initially diagnosed with large-volume tumors often fail to meet the criteria for resection due to tumor size and major vessel invasion. Therefore, it is imperative to move beyond traditional single-modality treatments and develop effective therapies through multidisciplinary collaboration.