What question did this study set out to answer?

This review aims to synthesize evidence on how stigma impacts health-related quality of life and healthcare access for individuals with sickle cell disease globally.

July 31, 2026Pediatric Blood & Cancer

From Stigma to Suffering: Stigma, Health‐Related Quality of Life, and Healthcare Access in Sickle Cell Disease—A Global Systematic Review

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Authors

SDShakshi DahiyaIndian Council of Medical Research JSJayvardhan SinghDr. Ram Manohar Lohia Institute of Medical Sciences YKYadlapalli S. KusumaAll India Institute of Medical Sciences

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Implication

Systematic review highlights stigma's negative effects on healthcare access and quality of life in individuals with SCD, indicating the need for reform.

Key Points

This review aims to synthesize evidence on how stigma impacts health-related quality of life and healthcare access for individuals with sickle cell disease globally.
Conducted a systematic review following PRISMA 2020 guidelines.
Included 53 studies published between January 2010 and December 2025 from multiple databases.
Identified four key domains of stigma affecting healthcare experiences.
Stigma was consistently linked to reduced health-related quality of life.
Individuals faced delayed healthcare seeking and weakened patient–provider relationships due to stigma.
Stigma contributes to health inequities across different healthcare systems.

Cite This Study

Dahiya et al. (2026) studied this question.

synapsesocial.com/papers/6a6c4761747664a1aa73ca3f https://doi.org/10.1002/1545-5017.70470

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Implication

Systematic review highlights stigma's negative effects on healthcare access and quality of life in individuals with SCD, indicating the need for reform.

From Stigma to Suffering: Stigma, Health‐Related Quality of Life, and Healthcare Access in Sickle Cell Disease—A Global Systematic Review

Discussion

Member takes

Implication

Key Points

Cite This Study

From Stigma to Suffering: Stigma, Health‐Related Quality of Life, and Healthcare Access in Sickle Cell Disease—A Global Systematic Review

Discussion

Member takes

Implication

Key Points

Cite This Study

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