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December 8, 2025BloodOpen Access

Exploring the relationship between health-related stigma and perceived discrimination among adults with sickle cell disease

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Authors

MEMiriam O. EzenwaUniversity of FloridaCECharles EllisUniversity of Florida HealthLDLaurie DuckworthUniversity of Florida

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Overview

Cross-sectional analysis shows stigma correlates with perceived discrimination in adults with sickle cell disease, suggesting psychosocial support is needed.

Key Points

  • The study aims to explore the relationship between health-related stigma and perceived discrimination in adults with sickle cell disease.
  • Cross-sectional, correlational analysis conducted on 171 adults with sickle cell disease
  • Stigma measured using Measure of Sickle Cell Stigma
  • Perceived discrimination assessed with Perceived Discrimination Scale
  • Spearman's rank correlation used to analyze the data
  • Moderate positive correlation found between perceived discrimination and stigma (rho = 0.47, p < .001)
  • Strongest correlation observed with social exclusion (rho = 0.46) among MoSCS subscales
  • Findings highlight the need for interventions addressing stigma and discrimination to improve self-management.

Cite This Study

Ezenwa et al. (2025) studied this question.

synapsesocial.com/papers/69362f604fa91c937236dd4chttps://doi.org/10.1182/blood-2025-1090
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Also Consider

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  1. 1Impact of disease- and race-based discrimination in health care on pain outcomes among adults living with sickle cell disease in the United States: The mediating roles of internalized stigma and depressive symptoms.2024 · 3 citations
  2. 2From Stigma to Suffering: Stigma, Health‐Related Quality of Life, and Healthcare Access in Sickle Cell Disease—A Global Systematic Review2026
  3. 3Sickle Cell Disease‐Related Stigma: Quantitative Assessment From India2025 · 1 citations
  4. 4Does self-compassion moderate the relationship between stigma, pain and psychological well-being among people living with sickle cell disease in Ghana?2026
  5. 5Social isolation and patient-reported and healthcare utilization in adults with sickle cell disease2025