Key result
Ivabradine successfully reduced the sinus rate and prevented the recurrence of inappropriate ICD shocks over a 3-year follow-up period in an 87-year-old man with cardiac sarcoidosis.
Why the study?
Does ivabradine prevent inappropriate shock due to sinus tachycardia in a patient with cardiac sarcoidosis and a CRT-D?
Case Report (n=1)
No
Does ivabradine prevent inappropriate shock due to sinus tachycardia in a patient with cardiac sarcoidosis and a CRT-D?
Ivabradine may be an effective pharmacological strategy to prevent inappropriate ICD shocks driven by sinus tachycardia in patients where reprogramming detection zones is not feasible.
Answers are grounded in this paper and cite their sources.
Sarcoidosis may cause post-CRT-D LV dysfunction with inappropriate shocks; leaves open optimal device settings in inflammatory cardiomyopathy.
We herein report a case of left ventricular dysfunction due to cardiac sarcoidosis following cardiac resynchronization therapy defibrillator (CRT-D) in an 87-year-old man. He presented to our hospital after receiving shock therapy while conscious. Device interrogation revealed that inappropriate shock occurred due to sinus tachycardia. Due to the setting of a low ventricular tachycardia (VT) detection rate because of a history of slow VT, increasing the VT detection rate was not feasible. After initiation of treatment with ivabradine, the sinus rate decreased and there was no recurrence of inappropriate shock during a 3-year follow-up period. Ivabradine was effective for preventing inappropriate shock due to sinus tachycardia.
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Masuda et al. (2024) conducted a case report in Cardiac sarcoidosis with inappropriate ICD shock due to sinus tachycardia (n=1). Ivabradine vs. Pre-treatment baseline was evaluated on Recurrence of inappropriate ICD shock. Ivabradine successfully reduced the sinus rate and prevented the recurrence of inappropriate ICD shocks over a 3-year follow-up period in an 87-year-old man with cardiac sarcoidosis.
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