Key result
Resting heart rate was negatively correlated with peak oxygen consumption in patients with sinus rhythm (Ptrend<0.0001), but positively correlated in those with atrial fibrillation (Ptrend=0.032).
Why the study?
Does the relationship between resting heart rate and peak oxygen consumption differ between patients with atrial fibrillation and sinus rhythm?
Population
2160 consecutive patients undergoing cardiopulmonary exercise testing in a single-hospital cohort, divided…
Comparison
Resting heart rate in patients with atrial… vs Resting heart rate in patients with sinus rhythm
Design
Cohort
Authors
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Rhythm may modify resting heart rate–peak VO2 links; hypothesis-generating for tailored targets, pending randomized confirmation.
Cohort (n=2,160)
No
Does the relationship between resting heart rate and peak oxygen consumption differ between patients with atrial fibrillation and sinus rhythm?
p-value: p=<0.0001
The impact of resting heart rate on exercise capacity differs significantly between patients with atrial fibrillation and sinus rhythm, suggesting that optimal heart rate targets may need to be tailored by rhythm status.
Kato et al. (2016) conducted a cohort in Atrial fibrillation and sinus rhythm (n=2,160). Resting heart rate was evaluated on Percentage of predicted peak oxygen consumption (p=<0.0001). Resting heart rate was negatively correlated with peak oxygen consumption in patients with sinus rhythm (Ptrend<0.0001), but positively correlated in those with atrial fibrillation (Ptrend=0.032).
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