Key result
Increased body mass index was associated with statistically significant increases in liver, spleen, kidney, and heart weights, with differential cardiac effects between men and women.
Why the study?
How do body mass index and age affect organ weights in an older autopsy population?
Population
300 medical autopsy reports of older individuals with multiple comorbidities
Design
Cohort
Authors
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Updated BMI-adjusted organ weight references may aid autopsy interpretation; leaves open prospective validation in comorbid populations.
Observational (n=300)
How do body mass index and age affect organ weights in an older autopsy population?
Increased BMI is associated with increased heart weight and ventricular wall thickness in women, suggesting obesity may have a greater impact on cardiovascular causes of death in women than men.
Mandal et al. (2012) conducted an observational in Medical autopsy population with multiple comorbidities (n=300). Body mass index (BMI) and age was evaluated on Organ weights (liver, spleen, kidneys, heart, thyroid). Increased body mass index was associated with statistically significant increases in liver, spleen, kidney, and heart weights, with differential cardiac effects between men and women.
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