What is the clinical evidence from this study?

Study design: Cohort. Population: Elective coronary artery bypass operations (CABG) (n=1023). Intervention: Perioperative myocardial ischemia vs. Absence of perioperative myocardial ischemia. Primary outcome: Postoperative myocardial infarction (PMI).

What question did this study set out to answer?

This research aims to identify the relationship between perioperative myocardial ischemia and the incidence of postoperative myocardial infarction.

February 1, 1985AnesthesiologyOpen Access

Does Perioperative Myocardial Ischemia Lead to Postoperative Myocardial Infarction?

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Key result

Perioperative myocardial ischemia was associated with a nearly threefold higher rate of postoperative myocardial infarction compared to patients without ischemia (6.9% vs. 2.5%).

Why the study?

Does perioperative myocardial ischemia increase the risk of postoperative myocardial infarction in patients undergoing elective CABG?

Population

1,023 patients undergoing elective coronary artery bypass operations (CABG)

Comparison

Presence of perioperative myocardial ischemia vs Absence of perioperative myocardial ischemia

Design

Cohort

Authors

SSStephen SlogoffLoyola University Chicago AKArthur S. KeatsBrigham and Women's Hospital

Discussion

Member takes

Implication

May link intraoperative ischemia to PMI in CABG; leaves open causal role and monitoring impact.

Key Points

This research aims to identify the relationship between perioperative myocardial ischemia and the incidence of postoperative myocardial infarction.
Nonparticipating observers recorded ECG and hemodynamic events during 1,023 elective coronary artery bypass operations (CABG).
Data on preoperative characteristics, quality of operation, and ischemic cardiac arrest duration were analyzed for risk factor relationships with postoperative myocardial infarction.
ECG ischemia, defined by ST segment depression ≥0.1 mV, was recorded along with related hemodynamic stability features.
ECG ischemia occurred in 36.9% of patients with myocardial infarction almost three times more frequent in those with ischemia (6.9% vs. 2.5%).
Ischemia was significantly related to tachycardia but not to hypertension or hypotension.
Suboptimal operational quality and prolonged ischemic cardiac arrest were significant risk factors for postoperative myocardial infarction, independent of ischemic events.

Study Design

Type

Cohort (n=1,023)

Structured PICO

Does perioperative myocardial ischemia increase the risk of postoperative myocardial infarction in patients undergoing elective CABG?

Population

1,023 patients undergoing elective coronary artery bypass operations (CABG).

Exposure

Presence of perioperative myocardial ischemia (defined as ST segment depression greater than or equal to 0.1 mV)

Comparator

Absence of perioperative myocardial ischemia

Outcome

Postoperative myocardial infarction (PMI)hard clinical

Main Result

Absolute Event Rate: 6.9% vs 2.5%

Perioperative myocardial ischemia is a common, independent risk factor for postoperative myocardial infarction in patients undergoing elective CABG, emphasizing the critical role of perioperative hemodynamic management.

Cite This Study

Slogoff et al. (1985) conducted a cohort in Elective coronary artery bypass operations (CABG) (n=1,023). Perioperative myocardial ischemia vs. Absence of perioperative myocardial ischemia was evaluated on Postoperative myocardial infarction (PMI). Perioperative myocardial ischemia was associated with a nearly threefold higher rate of postoperative myocardial infarction compared to patients without ischemia (6.9% vs. 2.5%).

synapsesocial.com/papers/6a6c7d24a528af2d65c283cc https://doi.org/10.1097/00000542-198502000-00002

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Does Perioperative Myocardial Ischemia Lead to Postoperative Myocardial Infarction?

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Does Perioperative Myocardial Ischemia Lead to Postoperative Myocardial Infarction?

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider