Why the study?
Does intermittent aortic cross-clamping compared to cold chemical cardioplegia affect the incidence of perioperative myocardial infarction in patients undergoing coronary artery bypass surgery?
Population
199 consecutive patients undergoing coronary artery bypass surgery
Comparison
Intermittent aortic cross-clamping (n=44) vs Cold chemical cardioplegia
Design
Cohort
Follow-up
Postoperative period (up to 18 hours for biomarkers)
Authors
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Confirms enzyme elevation with definite PMI after CABG; leaves open whether cross-clamping or cardioplegia affects incidence.
Does intermittent aortic cross-clamping compared to cold chemical cardioplegia affect the incidence of perioperative myocardial infarction in patients undergoing coronary artery bypass surgery?
Perioperative myocardial infarction during CABG is associated with significantly elevated CK-MB and LD1 levels, with risk factors including age ≥60, coronary endarterectomies, and prolonged bypass time.
Järvinen et al. (1983) studied this question.
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