Key result
Electrophysiologic stress testing revealed latent His-Purkinje conduction abnormalities in 20% (7 of 35) of children 1-8 years after surgical repair of congenital heart defects.
Why the study?
Does electrophysiologic stress testing reveal latent His-Purkinje conduction abnormalities in children after surgical repair of congenital heart defects?
Observational (n=35)
Does electrophysiologic stress testing reveal latent His-Purkinje conduction abnormalities in children after surgical repair of congenital heart defects?
Electrophysiologic stress testing can reveal latent His-Purkinje conduction abnormalities in children after surgical repair of congenital heart defects that may be missed on standard recordings.
May detect underrecognized conduction disease after congenital repair; hypothesis-generating for targeted electrophysiologic screening.
Conduction abnormalities of the His-Purkinje (HP) system are common sequelae of surgical repair of heart defects. Standard electrophysiologic recordings may fail to demonstrate abnormalities of the HP system when routine intervals are measured. When the conduction system is stressed, certain HP features that may indicate latent conduction disease within the HP system can be revealed. These features include split His potentials (SH) with spontaneous tachycardia or during rapid atrial pacing (RAP); SH with atrial ex- trastimuli (AES); and long HV intervals with AES associated with block distal to His during RAP. These find- ings may represent pathologic or functional properties of the HP system, and were identified in seven of 35 patients after surgical repair of tetralogy of Fallot (29 patients) or ventricular septal defect (six patients) who had electrophysiologic studies 1-8 years after operation. In five of the seven patients, these findings were revealed only when the conduction system was stressed. This incidence does not represent the true frequency of these features in the 35 patients because they were not evaluated under the same electrophysiologic stresses. Clinically, these patients did not differ from those manifesting these HP findings. The electrocardiographic patterns were as follows: normal QRS duration and normal axis (n = 1), right bundle branch block (RBBB) and normal axis (n = 1), RBBB and right-axis deviation (n = 4) (left anterior fascicular block (LAB] with tachycardia developed in one), RBBB and LAB (n = 1). The LAB was diagnosed on the basis of superior axis shift compared with the preoperative tracings. All had normal PR intervals.
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Wolff et al. (1980) conducted an observational in Post-surgical repair of tetralogy of Fallot or ventricular septal defect (n=35). Electrophysiologic stress testing was evaluated on Latent His-Purkinje conduction abnormalities. Electrophysiologic stress testing revealed latent His-Purkinje conduction abnormalities in 20% (7 of 35) of children 1-8 years after surgical repair of congenital heart defects.
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