Key result
Epicardial averaged lead recordings reliably detect His-Purkinje system activity during acute conduction disorders in preclinical models.
Why the study?
The sensitivity of extracardiac averaged recordings to changes in His-Purkinje system activation during conduction disorders was not well characterized.
Does epicardial averaged lead recording detect changes in His-Purkinje system activation during conduction disorders in a canine model?
Population
15 dogs undergoing thoracotomy
Comparison
Epicardial averaged lead recordings vs standard ECG and His bundle electrogram
Design
Preclinical experimental study with induced conduction disorders
Authors
Loading...
Does not support clinical use; leaves open translation of epicardial His-Purkinje detection to humans.
Does epicardial averaged lead recording detect changes in His-Purkinje system activation during conduction disorders in a canine model?
Epicardial averaged lead recordings can reliably detect and characterize His-Purkinje system activity during normal conduction and various experimentally induced conduction disorders in a canine model.
Berbari et al. (1975) studied Conduction disorders and junctional rhythms (n=15). Epicardial averaged lead (EAL) recordings vs. Standard ECG and His bundle electrogram was evaluated on Detection of His-Purkinje system activity and its alterations during conduction disorders. Epicardial averaged lead recordings in dogs consistently detected His-Purkinje system activity and its alterations during experimentally produced conduction disorders.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: