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November 1, 1973CirculationOpen Access

Noninvasive Technique for Detection of Electrical Activity During the P-R Segment

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Why the study?

Does signal averaging of surface leads accurately detect His-Purkinje electrical activity compared to intracardiac recordings in an animal model?

Population

15 anesthetized dogs

Comparison

Signal averaging of highly amplified, filtered… vs Intracardiac His bundle electrograms

Design

Preclinical

Authors

EBEdward J. BerbariIndiana University – Purdue University IndianapolisRLRalph LazzaraElectrophysiologyPSPhilip SametBaptist Hospital of Miami

Discussion

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Implication

Supports noninvasive His-Purkinje detection in animal models; leaves open human validation before clinical use.

Structured PICO

Does signal averaging of surface leads accurately detect His-Purkinje electrical activity compared to intracardiac recordings in an animal model?

P
Population
15 anesthetized dogs
I
Intervention
Signal averaging of highly amplified, filtered bipolar chest leads
C
Comparator
Intracardiac His bundle electrograms
O
Outcome
Correlation of preventricular activity (G complex) time intervals with His bundle electrogram (H-V times)surrogate

Signal averaging allows for the noninvasive detection of His-Purkinje system electrical activity from the body surface, correlating closely with invasive intracardiac recordings.

Cite This Study

Berbari et al. (1973) studied this question.

synapsesocial.com/papers/6a87d59f6841b83273ad2f3ehttps://doi.org/10.1161/01.cir.48.5.1005
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