Key result
Retrograde His activation occurs predominantly via the left bundle branch during RV premature stimulation in ~67% of cases.
Why the study?
The routes of retrograde impulse propagation in the His-Purkinje system during right ventricular premature stimulation were not fully characterized in patients with normal intraventricular conduction.
Population
24 patients with normal intraventricular conduction
Comparison
Retrograde conduction via left bundle branch vs right bundle branch vs both
Design
Observational study using intracardiac His bundle and right bundle branch recordings
Authors
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Variable retrograde His activation during RV stimulation warrants consideration in EP studies; leaves open its role in reentry and clinical outcomes.
Observational (n=24)
Retrograde activation of the His bundle during right ventricular premature stimulation occurs predominantly through the left bundle branch, though routes can vary within the same patient.
Akhtar et al. (1979) conducted an observational in Normal intraventricular conduction (n=24). Right ventricular extrastimuli was evaluated on Route of retrograde His bundle activation (H2). During right ventricular premature stimulation, retrograde His bundle activation occurred exclusively through the left bundle branch in 67% of cases and the right bundle branch in 12%.
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