Key result
Broad spectrum anti-inflammatory approaches and immune modulation show potential for improving outcomes in select heart failure patients, whereas highly specific strategies have failed.
Why the study?
Does anti-inflammatory therapy improve outcomes in patients with chronic heart failure?
Does anti-inflammatory therapy improve outcomes in patients with chronic heart failure?
While highly specific anti-inflammatory therapies have failed in heart failure, broad-spectrum immune modulation may offer therapeutic benefits for select patients and warrants further large-scale investigation.
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Inflammation-directed therapies in chronic HF remain unproven; leaves open whether IVIG, plasmapheresis, or immuno-adsorption improve outcomes.
Celis et al. (2008) conducted a review in chronic heart failure. anti-inflammatory therapy was evaluated. Broad spectrum anti-inflammatory approaches and immune modulation show potential for improving outcomes in select heart failure patients, whereas highly specific strategies have failed.
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