Key result
Depression is linked to ~3.7-fold higher medication non-adherence in heart failure patients.
Why the study?
The study was conducted to identify the factors contributing to medication non-adherence among patients with heart failure.
What factors are associated with medication non-adherence in patients with heart failure?
Cross-Sectional (n=340)
No
What factors are associated with medication non-adherence in patients with heart failure?
Identifying modifiable and non-modifiable factors like depression, alcohol use, and poor self-care can help clinicians target interventions to improve medication adherence in heart failure patients.
Answers are grounded in this paper and cite their sources.
Depression may flag non-adherence risk in HF outpatients; leaves open whether treating it improves adherence in prospective trials.
OBJECTIVE: to identify the factors contributing to medication non-adherence among patients with heart failure. METHOD: cross-sectional and analytical study using the Medida de Adesão ao Tratamento [Treatment Adherence Measure] scale to assess medication non-adherence. Independent variables were collected using the European Heart Failure Self-care Behavior Scale and an instrument developed by the authors based on a previous study. Statistical tests were implemented to analyze data with p≤0.05 statistical significance. RESULTS: the sample comprised 340 patients, with 9.4% considered non-adherent. The multiple analysis results showed that one unit increase in an individual's self-care score led to an 8% increase in the prevalence of non-adherence; patients with a family income above three times the minimum wage presented a prevalence of non-adherence equal to 3.5% of the prevalence of those with up to one times the minimum wage; individuals consuming alcohol or with depression presented 3.49 and 3.69 times higher prevalence of non-adherence, respectively, than individuals not presenting such history. CONCLUSION: medication non-adherence was associated with self-care, family income, depression, and alcohol consumption.
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Lima et al. (2024) conducted a cross-sectional in Heart Failure (n=340). Depression vs. No depression was evaluated on Medication non-adherence (PR 3.695, 95% CI 1.538-8.876, p=0.003). Depression was significantly associated with increased medication non-adherence compared to no depression (PR 3.695, 95% CI 1.538-8.876, p=0.003) in patients with heart failure.
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