Key result
Accumulating risk factors linked to ~162% higher odds of poor medication adherence in heart failure.
Why the study?
Medication nonadherence is a major cause of hospitalization in heart failure patients, and better identification of risk factors for poor adherence is needed.
Observational (n=218)
Odds Ratio: 2.62 (95% CI 1.78–3.86)
p-value: p=<0.001
In patients with heart failure, older age, recent diagnosis, multiple comorbidities, polypharmacy, and poor sleep quality interact to significantly increase the risk of poor medication adherence.
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Risk factors were associated with poor adherence in HF; hypothesis-generating for targeted interventions but should not yet change practice.
Riegel et al. (2020) conducted an observational in Heart failure (n=218). Unit increase in the number of risk factors was evaluated on Poor medication adherence (OR 2.62, 95% CI 1.78-3.86, p=<0.001). A unit increase in risk factors (comorbidities, polypharmacy, poor sleep) increased the odds of poor medication adherence in heart failure patients (OR 2.62; 95% CI 1.78-3.86; P<0.001).
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