Among adults with chronic kidney disease, only 37% had adequately controlled blood pressure (<130/80 mm Hg), with lack of control primarily attributable to isolated systolic hypertension.
Cross-Sectional (n=3,213)
Yes
Hypertension control is poor among US adults with CKD, driven primarily by isolated systolic hypertension, suggesting future guidelines and therapies should target this specific issue.
Although improved control of hypertension is known to attenuate progression of chronic kidney disease (CKD), little is known about the adequacy of hypertension treatment in adults with CKD in the United States. Using data from the Fourth National Health and Nutrition Survey, we assessed adherence to national hypertension guideline targets for patients with CKD (blood pressure 30 microg/mg). Multivariable logistic regression with appropriate weights was used to determine predictors of inadequate hypertension control and related outcomes. Among 3213 participants with CKD, 37% had blood pressure 130 mm Hg, with diastolic 80 mm Hg, with systolic blood pressure 75 years (OR, 4.7; 95% CI, 2.7 to 8.2), and albuminuria (OR, 2.4; 95% CI, 1.4 to 4.1) were independently associated with inadequate blood pressure control. We conclude that control of hypertension is poor in participants with CKD and that lack of control is primarily attributable to systolic hypertension. Future guidelines and antihypertensive therapies for patients with CKD should target isolated systolic hypertension.
Peralta et al. (Tue,) conducted a cross-sectional in Chronic Kidney Disease and Hypertension (n=3,213). Patient characteristics (e.g., age >75 years, non-Hispanic black race, albuminuria) was evaluated on Blood pressure <130/80 mm Hg (95% CI 34.5 to 41.8). Among adults with chronic kidney disease, only 37% had adequately controlled blood pressure (<130/80 mm Hg), with lack of control primarily attributable to isolated systolic hypertension.