Key result
Underweight first-time ICD recipients had significantly higher odds of in-hospital complications compared with normal weight patients (5.2% vs 2.3%; OR 2.15; 95% CI 1.68-2.75; P<0.0001).
Why the study?
Does underweight or obese body mass index increase the risk of in-hospital adverse events and mortality in first-time ICD recipients?
Cohort (n=83,312)
Yes
Does underweight or obese body mass index increase the risk of in-hospital adverse events and mortality in first-time ICD recipients?
Odds Ratio: 2.15 (95% CI 1.68–2.75)
Absolute Event Rate: 5.2% vs 2.3%
p-value: p=<0.0001
Underweight, but not obese, patients undergoing first-time ICD implantation are at significantly higher risk for periprocedural complications and in-hospital mortality compared to normal-weight patients.
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Underweight patients may warrant extra caution at ICD implant; registry data leave open whether BMI modification alters outcomes.
Hsu et al. (2012) conducted a cohort in First-time ICD recipients (n=83,312). Underweight (BMI ≤ 18.5 kg/m2) vs. Normal weight patients was evaluated on In-hospital complications (OR 2.15, 95% CI 1.68 to 2.75, p=<0.0001). Underweight first-time ICD recipients had significantly higher odds of in-hospital complications compared with normal weight patients (5.2% vs 2.3%; OR 2.15; 95% CI 1.68-2.75; P<0.0001).
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