Alcohol Consumption in Relation to Aortic Stiffness and Aortic Wave Reflections: A Cross-Sectional Study in Healthy Postmenopausal Women
Key result
Among healthy postmenopausal women, consuming 10 to 14 glasses of alcohol per week was associated with a lower mean pulse-wave velocity compared with nondrinkers (MD -0.869 m/s; 95% CI -1.44 to -0.29).
Why the study?
Does alcohol consumption improve aortic stiffness and wave reflections in healthy postmenopausal women?
Population
371 healthy postmenopausal women aged 50 to 74 years sampled from a population-based study
Comparison
Alcohol consumption vs Nondrinkers
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May link moderate alcohol to better arterial properties; hypothesis-generating and should not yet change practice.
Study Design
Type
Cross-Sectional (n=371)
Structured PICO
Does alcohol consumption improve aortic stiffness and wave reflections in healthy postmenopausal women?
P
Population
371 healthy postmenopausal women aged 50 to 74 years sampled from a population-based study.
E
Exposure
Alcohol consumption (categorized as 1 to 3, 4 to 9, 10 to 14, and 15 to 35 glasses of alcoholic beverages per week)
C
Comparator
Nondrinkers
O
Outcome
Aortic pulse-wave velocity and augmentation index assessed by applanation tonometrysurrogate
Main Result
Mean Difference: -0.869 (95% CI -1.44–-0.29)
Cite This Study
Sierksma et al. (2003) conducted a cross-sectional in Healthy (n=371). Alcohol consumption vs. Nondrinkers was evaluated on Mean pulse-wave velocity (MD -0.869 m/s, 95% CI -1.44 to -0.29). Among healthy postmenopausal women, consuming 10 to 14 glasses of alcohol per week was associated with a lower mean pulse-wave velocity compared with nondrinkers (MD -0.869 m/s; 95% CI -1.44 to -0.29).