Key result
Influenza B infection had similar clinical features to Influenza A overall, but was associated with more lower respiratory tract infections (P=0.034) and hospitalizations (P=0.001) in children ≤2 years.
Why the study?
Information on clinical differences among pediatric patients infected with the four recently circulating influenza viruses was sparse.
Are there clinical differences among pediatric patients infected with different circulating influenza viruses?
Population
1,588 patients with FluA and 964 patients with FluB aged <20 years
Comparison
FluA vs FluB, and dominant subtypes/lineages within FluA and FluB
Design
Retrospective medical record review
Authors
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Clinical features may differ by strain in children; leaves open need for strain-specific management.
Observational (n=2,552)
Are there clinical differences among pediatric patients infected with different circulating influenza viruses?
Clinical features of influenza in pediatric patients are generally similar across virus types, though Influenza B may cause more severe illness in children aged ≤2 years.
Han et al. (2021) conducted an observational in Influenza (n=2,552). Influenza B virus infection vs. Influenza A virus infection was evaluated on Clinical features, diagnoses, and outcomes. Influenza B infection had similar clinical features to Influenza A overall, but was associated with more lower respiratory tract infections (P=0.034) and hospitalizations (P=0.001) in children ≤2 years.
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