Key result
Statin therapy was associated with better 24-h ambulatory blood pressure control in essential hypertensive patients (OR 1.8; P<0.001).
Why the study?
Statin therapy was associated with lower blood pressure in some but not all previous studies.
Does statin therapy improve ambulatory blood pressure control in essential hypertensive patients?
Population
1827 consecutive essential hypertensive patients evaluated with 24-h ambulatory BP monitoring
Comparison
Statin therapy vs no statin therapy
Design
Retrospective observational propensity score-matched study
Authors
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Statin therapy was associated with better ambulatory BP control; leaves open causality and practice change pending randomized trials.
Observational (n=1,827)
Does statin therapy improve ambulatory blood pressure control in essential hypertensive patients?
Odds Ratio: 1.8
p-value: p=<0.001
Statin therapy is associated with significantly better 24-hour ambulatory blood pressure control in patients with essential hypertension, independent of antihypertensive treatment intensity.
Spannella et al. (2019) conducted an observational in essential hypertension (n=1,827). Statin therapy vs. no statin therapy was evaluated on 24-h BP control (OR 1.8, p=<0.001). Statin therapy was associated with better 24-h ambulatory blood pressure control in essential hypertensive patients (OR 1.8; P<0.001).
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