Key result
Organ-preserving surgical removal of a 25 kg giant retroperitoneal liposarcoma was performed; local recurrence at 16 months was treated surgically with no further recurrence at 12 months.
Case Report (n=1)
Complete resection with organ preservation is feasible for giant retroperitoneal liposarcomas, though close follow-up is required due to recurrence risk.
Giant retroperitoneal liposarcomas may remain asymptomatic despite kidney encasement; leaves open optimal detection and resection strategies.
Retroperitoneal liposarcoma is a rare tumor. The dimension and weight of liposarcoma are variable; those over 20 kg are called 'giant liposarcoma'. Herein, we report giant retroperitoneal liposarcoma measuring 45 cm in diameter and 25 kg in weight encasing the entire left kidney and adherent to adjacent structures. A 71-year-old woman presented for a regular checkup. Image study revealed a huge mass probably indicative of retroperitoneal liposarcoma encasing the entire left kidney and adherent to adjacent structures. We performed an organ-preserving surgical removal. The pathologic report was liposarcoma. At postoperative month 16, a follow-up CT revealed a locally recurrent tumor. The patient underwent surgical removal of the newly discovered mass. After the second surgery, the patient underwent regular follow-up CT for approximately 12 months, and to date, there has been no evidence of tumor recurrence. High-grade liposarcoma shows sensitivity to radiation therapy. However, the toxic effect of radiation therapy limits this option by treatment modality. The use of chemotherapy is also controversial. As a result, complete resection is the gold standard treatment. Here, we report a giant retroperitoneal liposarcoma encasing the entire left kidney and adherent to adjacent structures, describe successful organ-preserving surgical removal and discuss prognosis.
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Oh et al. (2016) conducted a case report in Giant retroperitoneal liposarcoma (n=1). Organ-preserving surgical removal was evaluated on Tumor recurrence. Organ-preserving surgical removal of a 25 kg giant retroperitoneal liposarcoma was performed; local recurrence at 16 months was treated surgically with no further recurrence at 12 months.
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