Key result
Adenosine (74.4%) and verapamil (81.8%) were similarly effective in terminating PSVT (P=0.45), both outperforming carotid sinus massage (32.4%, P<0.001), with success rates dependent on heart rate.
Why the study?
Does heart rate predict the success of adenosine, verapamil, and carotid sinus massage in terminating symptomatic PSVT in adults?
Population
106 adult patients with symptomatic paroxysmal supraventricular tachycardia (PSVT)
Comparison
Adenosine, verapamil, or carotid sinus massage vs Comparison between the three treatments
Design
Cohort
Follow-up
Immediate/acute
Authors
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Heart rate during PSVT can predict the likelihood of successful termination, with adenosine being more effective at faster rates (>173 bpm) and verapamil more effective at slower rates.
Observational (n=106)
Does heart rate predict the success of adenosine, verapamil, and carotid sinus massage in terminating symptomatic PSVT in adults?
Absolute Event Rate: 74.4% vs 32.4%
p-value: p=0.00032
Heart rate during PSVT can predict the likelihood of successful termination, with adenosine being more effective at faster rates (>173 bpm) and verapamil more effective at slower rates.
Piercarlo Ballo (2004) conducted an observational in Symptomatic paroxysmal supraventricular tachycardia (PSVT) (n=106). Adenosine and verapamil vs. Carotid sinus massage was evaluated on Termination of symptomatic episodes of paroxysmal supraventricular tachycardia (p=0.00032). Adenosine (74.4%) and verapamil (81.8%) were similarly effective in terminating PSVT (P=0.45), both outperforming carotid sinus massage (32.4%, P<0.001), with success rates dependent on heart rate.
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