February 1, 1977Journal of Applied Physiology
Ventilatory and gas exchange dynamics in response to sinusoidal work
Key result
Sinusoidal work on a cycle ergometer yielded time constants for VE, VCO2, VO2, and HR averaging 1.4, 1.2, 0.8, and 0.8 min, respectively, with VE and VCO2 strongly correlated (r = 0.97).
Population
5 subjects
Design
Other
Follow-up
30 min
Authors
Discussion
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Implication
May inform research models of exercise ventilatory control; leaves open clinical translation pending validation.
Structured PICO
P
Population
5 subjects who exercised on a cycle ergometer for 30 minutes at sinusoidally fluctuating work rates.
I
Intervention
Exercise on a cycle ergometer for 30 min at work rates fluctuating sinusoidally between 25 W and 80% of the anaerobic threshold at sinusoidal periods of 0.7, 1, 2, 4, 6, and 10 min
O
Outcome
Amplitude and phase relations between ventilation/gas exchange variables (VE, VCO2, VO2, HR) and perturbing work loadsurrogate
Main Result
Effect estimate: r = 0.97
Exercise hyperpnea appears linked to metabolism via carbon dioxide production, as evidenced by strongly correlated time constants for ventilation and CO2 production during sinusoidal exercise.
Cite This Study
Casaburi et al. (1977) studied this question. Sinusoidal work on a cycle ergometer was evaluated on Time constants for VE, VCO2, VO2, and HR (r = 0.97). Sinusoidal work on a cycle ergometer yielded time constants for VE, VCO2, VO2, and HR averaging 1.4, 1.2, 0.8, and 0.8 min, respectively, with VE and VCO2 strongly correlated (r = 0.97).