Coupling of ventilation to pulmonary gas exchange during nonsteady-state work in men

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Population

7 normal male subjects

Design

Other

Authors

Discussion

Supports CO2-linked ventilatory control during moderate exercise; leaves open translation to clinical populations.

Population

7 normal male subjects

Intervention

Constant-load cycle ergometry to a series of subanaerobic threshold work rates (eight 6-min periods of alternating loaded and unloaded cycling)

Outcome

Dynamics of ventilatory coupling to CO2 output (VCO2) and O2 uptake (VO2)surrogate

Exercise hyperpnea is coupled to metabolism via a signal proportional to VCO2 in both nonsteady and steady states of moderate exercise.

Wasserman et al. (1983) studied this question.

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