Key result
High-sensitive troponin T improved early diagnostic accuracy for acute myocardial infarction compared with conventional troponins, achieving 99% sensitivity and 83% specificity at two hours.
Why the study?
Does high-sensitive troponin T improve early diagnostic accuracy for acute myocardial infarction compared to conventional troponins in chest pain patients without ST-elevations?
Population
n=233 consecutive chest pain patients without persistent ST-elevations
Comparison
Roche high-sensitive troponin T assay measured… vs Conventional troponin assays measured on…
Design
Cohort
Follow-up
2 hours
Authors
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May support earlier MI detection with Hs-TnT at 2 hours; hypothesis-generating in observational cohort, needs prospective validation.
Observational (n=233)
Does high-sensitive troponin T improve early diagnostic accuracy for acute myocardial infarction compared to conventional troponins in chest pain patients without ST-elevations?
High-sensitive troponin T improves early diagnostic accuracy for acute myocardial infarction compared to conventional assays, allowing for rapid rule-out within the first few hours of admission.
Melki et al. (2011) conducted an observational in Chest pain without ST-elevations (n=233). Roche high-sensitive troponin T (Hs-TnT) vs. Conventional troponins (Roche troponin T fourth generation and Beckman Coulter Accu-TnI) was evaluated on Early diagnostic value for acute Myocardial Infarction (MI). High-sensitive troponin T improved early diagnostic accuracy for acute myocardial infarction compared with conventional troponins, achieving 99% sensitivity and 83% specificity at two hours.
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