Key result
Organic mitral regurgitation was associated with lower mitral annular area fractional change compared to controls (22% vs 28%, P<0.001), which correlated with MR severity and left atrial function.
Case-Control (n=104)
Absolute Event Rate: 22% vs 28%
p-value: p=<0.001
In patients with organic mitral regurgitation, reduced mitral annular function correlates with MR severity and left atrial size and function, but not with left ventricular function.
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MA dysfunction correlates with MR severity and LA remodeling in OMR; leaves open whether 3D echo MA assessment refines risk stratification.
Mihaila et al. (2016) conducted a case-control in Organic mitral regurgitation (n=104). Organic mitral regurgitation vs. Controls was evaluated on Mitral annular area fractional change (p=<0.001). Organic mitral regurgitation was associated with lower mitral annular area fractional change compared to controls (22% vs 28%, P<0.001), which correlated with MR severity and left atrial function.
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