November 25, 2011Heart
Five-minute heart rate variability can predict obstructive angiographic coronary disease
Key result
Low frequency heart rate variability <250 ms² was strongly predictive of obstructive coronary artery disease on angiography (adjusted OR 2.42; 95% CI 1.33-4.38; p=0.004).
Why the study?
Does five-minute heart rate variability predict obstructive coronary artery disease in patients undergoing elective angiography?
Population
470 consecutive patients undergoing elective angiography, regardless of co-morbidity, across three cardiac…
Design
Cohort
Authors
Discussion
Loading...
Member takes
Implication
Hypothesis-generating for HRV in CAD risk stratification; should not yet change practice.
Study Design
Type
Observational (n=470)
Multicenter
Yes
Structured PICO
Does five-minute heart rate variability predict obstructive coronary artery disease in patients undergoing elective angiography?
P
Population
470 consecutive patients undergoing elective angiography with predominantly normal cardiac rhythm.
E
Exposure
Five-minute heart rate variability (HRV) assessment
O
Outcome
Presence of obstructive CAD (≥50% stenosis) on angiographysurrogate
Main Result
Odds Ratio: 2.42 (95% CI 1.33–4.38)
p-value: p=0.004
Five-minute heart rate variability is a strong, independent predictor of obstructive coronary artery disease in patients undergoing elective angiography, potentially helping to reduce unnecessary invasive procedures.
Cite This Study
Kotecha et al. (2011) conducted an observational in Obstructive coronary artery disease (n=470). Low frequency heart rate variability <250 ms² vs. Low frequency heart rate variability ≥250 ms² was evaluated on Presence of obstructive CAD (≥50% stenosis) on angiography (OR 2.42, 95% CI 1.33-4.38, p=0.004). Low frequency heart rate variability <250 ms² was strongly predictive of obstructive coronary artery disease on angiography (adjusted OR 2.42; 95% CI 1.33-4.38; p=0.004).