Key result
Preoperative cognitive impairment was highly prevalent (28.61%) in elderly orthopedic patients, with atherosclerosis significantly increasing the risk (OR 2.367) alongside age, sleep disorders, and high cholesterol.
Why the study?
Preexisting cognitive impairment predicts poor postoperative outcomes in seniors, yet it remains underidentified and underdiagnosed in a large proportion of geriatric patients.
Cross-Sectional (n=374)
No
Odds Ratio: 2.367 (95% CI 1.169–4.794)
p-value: p=0.017
Preoperative cognitive impairment is highly prevalent (28.61%) in elderly orthopedic surgery patients, with age, sleep disorders, atherosclerosis, and high cholesterol identified as key risk factors.
May inform preoperative risk stratification in elderly orthopedic patients; cross-sectional evidence leaves open whether interventions improve outcomes.
BACKGROUND: Preexisting cognitive impairment is emerging as a predictor of poor postoperative outcomes in seniors. Nevertheless, cognitive impairment in a large proportion of geriatric patients has not been well identified and diagnosed. METHODS: This is a cross-sectional study. Mini-mental state examination scale was used to assess the cognitive function of elderly patients aged ≥65 years undergoing orthopedic surgery preoperatively. The baseline, living habits and laboratory examination results of two groups were compared, and a multivariable logistic regression model was used to identify independent predictors of preoperative cognitive impairment. RESULTS: A total of 374 elderly patients with orthopedic surgery indications met the inclusion criteria, and 28.61% of them had preoperative cognitive impairment. Multivariable logistic regression analysis showed that age (OR = 1.089, P < 0.001), subjective sleep disorders (OR = 1.996, P = 0.021), atherosclerosis (OR = 2.367, P = 0.017), and high cholesterol level (OR = 1.373, P = 0.028) were independent risk factors for preoperative cognitive impairment, while high education level performed as a protective factor (compared with the illiterate group, primary school group: OR = 0.413, P = 0.009; middle school or above group: OR = 0.120, P < 0.001). CONCLUSIONS: The prevalence of preoperative cognitive dysfunction in geriatric elective orthopedic surgical patients was high. Our study identified venerable age, low level of education, subjective sleep disorders, atherosclerosis, and high cholesterol level as risk factors for preoperative cognitive impairment in these patients. Understanding these risk factors contributes to assisting in prevention and directed interventions for the high-risk population.
No takes yet. Share an insight, caveat, or question.
Gan et al. (2020) conducted a cross-sectional in Preoperative cognitive impairment in orthopedic surgery (n=374). Atherosclerosis vs. No atherosclerosis was evaluated on Preoperative cognitive impairment (OR 2.367, 95% CI 1.169-4.794, p=0.017). Preoperative cognitive impairment was highly prevalent (28.61%) in elderly orthopedic patients, with atherosclerosis significantly increasing the risk (OR 2.367) alongside age, sleep disorders, and high cholesterol.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: