Key result
Preoperative cognitive impairment was present in 28.61% of elderly orthopedic patients, with atherosclerosis (OR 2.367), subjective sleep disorders (OR 1.996), and high cholesterol (OR 1.373) identified as independent risk factors.
Why the study?
Preexisting cognitive impairment predicts poor postoperative outcomes in seniors, but it remains poorly identified and diagnosed in a large proportion of geriatric patients.
What are the independent predictors of preoperative cognitive impairment in elderly patients undergoing orthopedic surgery?
Cross-Sectional (n=374)
No
What are the independent predictors of preoperative cognitive impairment in elderly patients undergoing orthopedic surgery?
Odds Ratio: 2.367 (95% CI 1.169–4.794)
p-value: p=0.017
Preoperative cognitive impairment is highly prevalent (28.61%) in elderly orthopedic surgery patients, with age, sleep disorders, atherosclerosis, and high cholesterol identified as key risk factors.
Supports preoperative cognitive screening in elderly orthopedic patients with identified risks; hypothesis-generating pending prospective validation.
Background Preexisting cognitive impairment is emerging as a predictor of poor postoperative outcomes in seniors. Nevertheless, cognitive impairment in a large proportion of geriatric patients has not been well identified and diagnosed.Methods This is a cross-sectional study. Mini-mental state examination scale was used to assess cognitive function of elderly patients aged ≥ 65 years undergoing orthopedic surgery preoperatively. The baseline, living habits and laboratory examination results of the two groups were compared, and multivariate Logistic regression model was used to identify independent predictors of preoperative cognitive impairment.Results A total of 374 elderly patients with orthopedics met the inclusion criteria, and 28.61% with preoperative cognitive impairment. Multivariate Logistic regression analysis showed that age (OR=1.089, P<0.001), subjective sleep disorders (OR=1.996, P=0.021), atherosclerosis (OR=2.367, P=0.017), high cholesterol level (OR=1.373, P=0.028) were independent risk factors for preoperative cognitive impairment, while high education level performed as a protective factor (Compared with illiterate group, primary school group: OR=-0.885, P=0.009; middle school or above group: OR=-2.118, P<0.001).Conclusions The prevalence of preoperative cognitive dysfunction in geriatric elective orthopedic surgical patients was high. Our study identified venerable age, low level of education, subjective sleep disorders, atherosclerosis, high cholesterol level as risk factors for preoperative cognitive impairment in these patients. Understanding these risk factors contribute to assist in prevention and directed interventions for the high-risk population.
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Gan et al. (2020) conducted a cross-sectional in Preoperative cognitive impairment in elderly orthopedic patients (n=374). Atherosclerosis vs. No atherosclerosis was evaluated on Preoperative cognitive impairment (OR 2.367, 95% CI 1.169-4.794, p=0.017). Preoperative cognitive impairment was present in 28.61% of elderly orthopedic patients, with atherosclerosis (OR 2.367), subjective sleep disorders (OR 1.996), and high cholesterol (OR 1.373) identified as independent risk factors.
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