Key result
Purification of Trypanosoma brucei RNPs identified four SL RNP proteins (27-36 kDa) and one U2 RNP protein (31 kDa), indicating different polypeptides associate with these RNAs.
Population
Trypanosoma brucei cells/extracts
Design
Preclinical
Authors
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Highlights distinct RNP associations in T. brucei; leaves open their mechanistic roles in trans-splicing.
The study identifies distinct protein compositions for SL and U2 RNPs in Trypanosoma brucei, providing insights into the trans-splicing machinery.
Michaeli et al. (1990) studied this question. Purification of SL and U2 RNPs was evaluated on Identification of RNP proteins. Purification of Trypanosoma brucei RNPs identified four SL RNP proteins (27-36 kDa) and one U2 RNP protein (31 kDa), indicating different polypeptides associate with these RNAs.
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